DNA replication occurs during this S (synthesis) phase. S Phase: To produce two similar daughter cells, the complete DNA instructions in the cell must be duplicated. (Click on the Checkpoints animation, above.) An important cell cycle control mechanism activated during this period (G1 Checkpoint) ensures that everything is ready for DNA synthesis. Gap 1 (G1): Cells increase in size in Gap 1, produce RNA and synthesize protein. An example of the latter is a cell that has reached an end stage of development and will no longer divide (e.g. This may be a temporary resting period or more permanent. Gap 0 (G0): There are times when a cell will leave the cycle and quit dividing. By studying molecular events in cells, scientists have determined that interphase can be divided into 4 steps: Gap 0 (G0), Gap 1 (G1), S (synthesis) phase, Gap 2 (G2). During this period, the cell is constantly synthesizing RNA, producing protein and growing in size. Interphase generally lasts at least 12 to 24 hours in mammalian tissue. Those interphase activities are indispensible in making the next mitosis possible. Interphase: Interphase, which appears to the eye to be a resting stage between cell divisions, is actually a period of diverse activities.
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